Author(s)

Lifeng Zhou and Rong Lu

Corresponding Author

Rong Lu

Abstract

Erythema nodosa is a common clinical disease, which is an inflammatory disease that mainly affects subcutaneous fat tissue, and it occurs in young and middle-aged women [1]. Clinical studies believe that [2], the etiology of erythema nodosa is complicated, such as infection, drugs, estrogen and other diseases, and it is clinically manifested as red or purple painful nodules. Previous studies have shown that the etiology of erythema nodosa is complicated, and common causes include: streptococcal infection, tuberculosis infection, drugs, delayed allergy, etc. (1) Streptococcal infection. Some patients may occur after respiratory infection, angina and acute tonsillitis [3]; (2) tuberculosis infection. More and more studies believe that erythema nodosa is closely related to tuberculosis infection. For patients with a positive result of the calcineurin test, the incidence of erythema nodosa is more than 60.0%, which is the body's allergy to tuberculosis or its toxin; (3) drugs. For long-term use of bromine agents, sulfa drugs and oral contraceptives, the incidence of erythema nodosa is higher [4]. (4) Delayed allergy. Skin allergies are caused by a variety of reasons, but the specific pathogenesis has not been clarified clinically [5]. Generalized erythema nodosa is rarely reported in clinical practice. 2 cases of generalized erythema nodosa treated in our department are reported as follows.

Keywords

Erythema Nodosa; Generalized