Author(s)

Lifeng Zhou and Rong Lu

Corresponding Author

Rong Lu

Abstract

Abstract: The objective is to investigate the diagnostic method and effect of acrokeratosis elastofiberoid disease. Method: One patient who was diagnosed with acrokeratinoid elastofibroidosis in our hospital in March 2018 was selected as the object. After admitted to our hospital, further examinations were conducted for the patient to understand the patients' past medical history so as to finally complete physical examination, and the examination in dermatology department was accomplished. Besides, histopathological examination of the skin was conducted for the patient and corresponding treatments were formulated according to the results of the examination. Results: Integration of the clinical manifestations and histopathological examination. Diagnosis:It was diagnosed with crokeratosis elastofiberoid. Treatment: The patient was advised to receive oral treatment with abretaic acid, but the patient failed to not receive treatment due to concerns on the side effect of the drug. Follow-up was not implemented. Conclusions: The acrokeratoid elastofibroidosis is a rarely seen disease and more examinations in skin histomathological examination will be conducive to make a definite diagnosis of the disease. Good results can be obtained by the treatment for patients with Averin acid. However, the incidence of adverse drug reactions is high, so vital signs monitoring for patients should be strengthened to promote the recovery of patients. Acrokeratinoelastic fibroidosis is a rare skin disease of keratinoelastic tissue degeneration in the hands and feet, also known as collagenous plaques of foot [1, 2].Previous studies have shown [2] that acrokeratinoid elastofibroidosis is most likely to occur in young or middle-aged people, and the patients were mostly around 20 years old, which has nothing to do with gender or race.At present, clinically, the pathogenesis of acrokeratinoid elastofibroidosis has not been clarified, Lesions mainly occur in the palmoplantar, the skin at the junction of dorsal and volar hand and foot, the line between thumb and index finger, also occur in the dorsal and nail bed of hand and foot joints in some patients, or in front of the shin and tibia, presenting a symmetrical distribution [4].Studies by domestic scholars have shown that[5]: Acrokeratinoid elastofiberosis is mostly scattered or densely distributed, and when it is densely distributed, presenting "paving stone" distribution,and thus affecting the functions of limbs and joints of patients.Therefore, it is of great significance to strengthen the diagnosis and treatment of patients with acrokeratosis elastofiberoid disease to improve the prognosis of patients.In this study, patients with acrokeratosis elastofibroidosis were selected as the objects to explore the diagnostic methods and effects of acrokeratosis elastofibroidosis, as reported below.

Keywords

Keyword: Elastofiberoid Disease; Acrokeratosis; Diagnostic Method; Avinoic Acid; Adverse Reactions